Prevención de infecciones asociadas a cuidados de la salud en pacientes quemados / Prevention of healthcare-associated Infections in burn patients

Las infecciones asociadas a cuidados de la salud (IACS) son una de las complicaciones más importantes que presentan los pacientes gran quemados. Aumentan su morbimortalidad, la duración de su estadía, el consumo de antimicrobianos y los costos hospitalarios. Las tasas reportadas de IACS son muy variables entre los distintos países y centros de atención.El ánimo de esta publicación es brindar el material necesa-rio y actualizado de las medidas de control de infecciones que se deben implementar en la atención de los quemados ya que no es fácil disponer de información sobre este tema.En la presente revisión se analizaron estudios de distin-tas poblaciones, adultos y niños, con diferentes tipos que-maduras y diversos lugares de atención. Se utilizó como material de referencia las recomendaciones vigentes de la Sociedad Internacional de injurias por Quemaduras (ISBI, por su sigla inglés) y se adicionaron publicaciones y expe-riencias de grupos de trabajo local e internacional referen-tes en el tema.Se describen cinco tipos de medidas de control y preven-ción de IACS: medidas generales, medidas de higiene am-biental, prevención de la infección de los lechos de las que-maduras, profilaxis antibiótica y medidas de prevención de neumonía, infecciones asociadas a catéteres vasculares y vesicales en quemados. Es esencial implementar un enfoque proactivo y multidisci-plinario del control de infecciones en la atención de estos pacientes, generando recomendaciones adaptadas a la realidad de cada centro de salud, destinadas a disminuir las transmisión cruzada de microorganismos, utilizar los antimicrobianos tópicos y sistémicos en forma adecuada, disminuir la multirresistencia, reducir las IACS y su mor-talidad

Healthcare-associated infections (HAIs) are one of the most important complications of severe burn patients. They increase their morbidity and mortality, length of stay, antimicrobial consumption, and hospital costs. Re-ported rates of IACS vary widely across countries and care settings.The purpose of this publication is to provide the nec-essary and up-to-date material on the infection control measures that should be implemented in the care of burn patients, since it is not easy to have information on this subject.In this review, we analysed studies of different popula-tions, adults and children, with different types of burns and different places of care. The current recommenda-tions of the International Society of Burn Injuries (ISBI) were used as reference material, and publications and experiences of local and international working groups on the subject were added. Five types of IACS control and prevention measures are described: General mea-sures, Environmental hygiene measures, Prevention of infection of burn injuries, Antibiotic prophylaxis and pre-vention measures for pneumonia, infections associated with vascular and bladder catheters in burn patients.Conclusion: It is essential to implement a proactive and multidisciplinary approach to infection control in the care of these patients, generating recommendations adapted to the reality of each health center, aimed at reducing cross-transmission of microorganisms, using typical and systemic antimicrobials appropriately, reduc-ing multiresistance, reducing HAIs and their mortality

La matriz extracelular en la curación de las heridas cutáneas. Aspectos físicos, químicos y biológicos / Extracellular matrix in healing of cutaneous wounds. Physical, chemical and biological aspects

Se revisan los nuevos conocimientos sobre la matriz extracelular (MEC), que han permitido descubrir su importante rol en la cicatrización de las heridas cutáneas. Se describen sus características morfofisiológicas y cómo interviene en la curación de las heridas cutáneas. Se presentan cuatro casos clínicos en los que se aplicó este enfoque terapéutico: los sustitutos de piel y la "cura húmeda"

We review the new knowledge about the extracellular ma-trix (ECM) that has allowed us to discover its important role in the healing of cutaneous wounds. The morpho-physiological characteristics of ECM and its role in the healing of cutaneous wounds are described. Four clinical cases are presented where this therapeutic approach was applied: the skin substitutes and the "moist wound healing".

Small Molecules Accelerate Skin Wound Healing: Shikonin Efficacy and Mechanism of Action in Mice / Las Moléculas Pequeñas Aceleran la Curación de Heridas en la Piel: Eficacia de Shikonin y Mecanismo de Acción en Ratones

SUMMARY: The objective of this study was to investigate the therapeutic wound healing potential and molecular mechanisms of shikonin as small molecules in vitro. A mouse burn model was used to explore the potential therapeutic effect of shikonin; we traced proliferating cells in vivo to locate the active area of skin cell proliferation. Through the results of conventional pathological staining, we found that shikonin has a good effect on the treatment of burned skin and promoted the normal distribution of skin keratin at the damaged site. At the same time, shikonin also promoted the proliferation of skin cells at the damaged site; importantly, we found a significant increase in the number of fibroblasts at the damaged site treated with shikonin. Most importantly, shikonin promotes fibroblasts to repair skin wounds by regulating the PI3K/AKT signaling pathway. This study shows that shikonin can effectively promote the proliferation of skin cell, and local injection of fibroblasts in burned skin can play a certain therapeutic role.

El objetivo de este trabajo fue investigar el potencial terapéutico de cicatrización de heridas y los mecanismos moleculares de la shikonina como moléculas pequeñas in vitro. Se utilizó un modelo de quemaduras en ratones para explorar el posible efecto terapéutico de la shikonina; Rastreamos las células en proliferación in vivo para localizar el área activa de proliferación de células de la piel. A través de los resultados de la tinción para patología convencional, encontramos que la shikonina tiene un buen efecto en el tratamiento de la piel quemada y promueve la distribución normal de la queratina de la piel en el sitio dañado. Al mismo tiempo, la shikonina también promovió la proliferación de células de la piel en el sitio dañado. Es importante destacar que encontramos un aumento significativo en la cantidad de fibroblastos en el sitio dañado tratado con shikonina. Lo más importante es que la shikonina promueve la función reparadora de fibroblastos en las heridas de la piel regulando la vía de señalización PI3K/ AKT. Este estudio muestra que la shikonina puede promover eficazmente la proliferación de células de la piel y que la inyección local de fibroblastos en la piel quemada puede desempeñar un cierto papel terapéutico.

Oral glutamine dipeptide or oral glutamine free amino acid reduces burned injury progression in rats / O dipeptídeo de glutamina oral ou aminoácido livre de glutamina oral reduz a progressão da lesão por queimadura em ratos

Abstract This study was carried out to evaluate the effect of Glutamine, as a dipeptide or a free amino acid form, on the progression of burn injuries in rats. Thirty male Wistar rats were burned with a comb metal plate heated in boiling water (98 °C) for three minutes, creating four rectangular full-thickness burn areas separated by three unburned interspaces (zone of stasis) in both dorsum sides. The animals were randomized into three groups (n=10): saline solution (G1-Control) and treated groups that orally received Glutamine as dipeptide (G2-Dip) or free amino acid (G3-FreeAA). Two and seven days after burn injury, lesions were photographed for unburned interspaces necrosis evolution assessment. Seven days after injury, glutathione seric was measured and histopathological analysis was performed. By photographs, there was a significant reduction in necrosis progression in G3-Free-AA between days two and seven. Histopathological analysis at day 7 showed a significantly higher stasis zone without necrosis and a higher number of fibroblasts in G2-Dip and G3-FreeAA compared with G1-Control. Also, glutathione serum dosage was higher in G2-Dip. The plasmatic glutathione levels were higher in the G2-Dip than the G1-Control, and there was a trend to higher levels in G3-FreeAA. The reduction in histological lesions, greater production of fibroblasts, and greater amounts of glutathione may have benefited the evolution of burn necrosis, which showed greater preservation of interspaces.

Resumo Este estudo foi realizado para avaliar o efeito da Glutamina, como um dipeptídeo ou forma de aminoácido livre, na progressão de queimaduras em ratos. Trinta ratos Wistar machos foram queimados com um pente de metal aquecido em água fervente (98 °C) por três minutos, criando quatro áreas retangulares queimadas separadas por três interesespaços não queimados (zona de estase) em ambos os lados do dorso. Os animais foram randomizados em três grupos (n = 10): solução salina (G1-Controle) e grupos tratados que receberam glutamina via oral como dipeptídeo (G2-Dip) ou aminoácido livre (G3-FreeAA). Dois e sete dias após a queimadura, as lesões foram fotografadas para avaliação da evolução da necrose entre os espaços não queimados. Sete dias após a lesão, foi dosada a glutationa sérica e realizada análise histopatológica. Pelas fotografias, houve uma redução significativa na progressão da necrose no G3-Free-AA entre os dias dois e sete. A análise histopatológica no dia 7 mostrou uma zona de estase significativamente maior sem necrose e número mais elevado de fibroblastos em G2-Dip e G3-FreeAA em comparação com G1-Controle. Os níveis plasmáticos de glutationa foram maiores no G2-Dip em relação ao G1-Controle, e houve tendência a níveis mais elevados no G3-FreeAA. A redução das lesões histológicas, maior produção de fibroblastos, maior quantidade de glutationa podem ter beneficiado a evolução da necrose da queimadura, que mostrou maior preservação dos interespaços.

Preclinical study of experimental burns treated with photobiomodulation and Human Amniotic Membrane, both isolated and associated / Estudo pré-clínico de queimaduras experimentais tratadas com fotobiomodulação e membrana amniótica humana, isoladas e associadas / Estudio preclínico de quemaduras experimentales tratadas con fotobiomodulación y membrana amniótica humana, solas y combinadas

Abstract Objective: to evaluate the effect of photobiomodulation with low-level 660 nm laser alone or associated with Human Amniotic Membrane in the repair of partial-thickness burns in rats. Method: an experimental study conducted with 48 male Wistar rats, randomized into four groups: Control, Human Amniotic Membrane, Low-Level Laser Therapy, and Low-Level Laser Therapy associated with Human Amniotic Membrane. The histopathological characteristics of the skin samples were analyzed 7 and 14 days after the burn. The data obtained were submitted to the Kolmogorov-Smirnov and Mann-Whitney tests. Results: the histological analysis of the burn injuries showed a decrease in inflammation (p<0.0001) and an increase in proliferation of fibroblasts (p<0.0001) mainly at 7 days in all treatments related to the control group. At 14 days, the greater effectiveness in accelerating the healing process was significant (p<0.0001) in the Low-Level Laser Therapy group associated with the Human Amniotic Membrane. Conclusion: the association of photobiomodulation therapies with the Human Amniotic Membrane allowed verifying a reduction in the healing process time of the experimental lesions, stimulating its proposal as a treatment protocol in partial-thickness burns.

Resumo Objetivo: avaliar o efeito da fotobiomodulação com laser de baixa intensidade 660 nm isoladamente ou associada à membrana amniótica humana no reparo de queimaduras de espessura parcial em ratos. Método: estudo experimental com 48 ratos Wistar machos, randomizados em quatro grupos: Controle, Membrana Amniótica Humana, Terapia a Laser de Baixa Intensidade e Terapia a Laser de Baixa Intensidade associado à Membrana Amniótica Humana. As características histopatológicas das amostras de pele foram analisadas aos 7 e 14 dias após a queimadura. Os dados obtidos foram submetidos aos testes de Kolmogorov-Smirnov e Mann Whitney. Resultados: a análise histológica das lesões por queimadura mostrou a diminuição da inflamação (p <0,0001) e aumento da proliferação de fibroblastos (p <0,0001), principalmente nos 7 dias em todos os tratamentos relacionados ao grupo controle. Aos 14 dias, a maior efetividade na aceleração do processo cicatricial foi significativa (p<0,0001) no grupo Terapia a Laser de Baixa Intensidade associado à Membrana Amniótica Humana. Conclusão: a associação das terapias de fotobiomodulação à membrana amniótica humana permitiu comprovar redução no tempo do processo cicatricial das lesões experimentais, estimulando sua proposição como protocolo de tratamento em queimaduras de espessura parcial.

Resumen Objetivo: evaluar el efecto de la fotobiomodulación con láser de baja intensidad 660 nm de sola o combinada con la membrana amniótica humana en la reparación de quemaduras de espesor parcial en ratas. Método: estudio experimental con 48 ratas Wistar macho, aleatorizadas en cuatro grupos: Control, Membrana Amniótica Humana, Terapia con Láser de Baja Intensidad y Terapia con Láser de Baja Intensidad combinada con la Membrana Amniótica Humana. Las características histopatológicas de las muestras de piel fueron analizadas a los 7 y 14 días después de la quemadura. Los datos obtenidos fueron sometidos a las pruebas de Kolmogorov-Smirnov y Mann-Whitney. Resultados: el análisis histológico de las lesiones por quemadura mostró una disminución de la inflamación (p <0,0001) y un aumento de la proliferación de fibroblastos (p <0,0001) principalmente a los 7 días en todos los tratamientos en comparación con el grupo control; a los 14 días, en el grupo de Terapia con Láser de Baja Intensidad combinada con la Membrana Amniótica Humana la mayor efectividad en la aceleración del proceso de cicatrización fue significativa (p<0,0001). Conclusión: la asociación de terapias de fotobiomodulación con la membrana amniótica humana permitió comprobar que hubo una reducción en el tiempo del proceso de cicatrización de lesiones experimentales, lo cual favorece que se proponga como protocolo de tratamiento en quemaduras de espesor parcial.

Validação de Conteúdo e Aplicabilidade de Protocolo de Cuidados de Enfermagem a Vítimas de Queimaduras / Validación de Contenido y Aplicabilidad de Un Protocolo de Atención de Enfermería a Víctimas de Quemaduras / Content Validation and Applicability of a Nursing Care Protocol for Burn Victims

Objetivos:Construir e validar um protocolo de cuidados de enfermagem a pacientes adultos que sofreram queimaduras em um hospital público na Região Norte do Brasil e avaliar sua aplicabilidade. Método: Estudo metodológico que seguiu as etapas: construção do instrumento; validação do conteúdo utilizando a ferramenta de avaliação Appraisal of Guidelines for Research & Evaluation II (AGREE II); e análise de aplicabilidade com questionário semiestruturado com a equipe de enfermagem e por concordância e teste de Kappa. Resultados: Na etapa diagnóstico situacional, o protocolo foi elaborado com base na revisão de literatura e validado pelos especialistas por meio do instrumento AGREE II, com valor de índice de validade de conteúdo geral de 0,93, e da análise de aplicabilidade com análise de teste de Kappa, obtendo o valor de 0,81, com a concordância quase perfeita. Conclusão: O protocolo foi estruturado com qualidade para guiar a equipe de enfermagem na assistência ao paciente queimado, e indica-se, portanto, a sua utilização.

Objective:To build and validate a nursing care protocol to adult patients who suffered burns in a public hospital in the North region of Brazil and evaluate its applicability. Method: Methodological study that followed the steps: construction of the instrument; content validation using the Appraisal of Guidelines for Research & Evaluation II (AGREE II) assessment tool; and applicability analysis with a semi-structured questionnaire with the nursing team and by agreement and Kappa test. Results: In the situational diagnosis stage, the protocol was elaborated based on the literature review and validated by the specialists through the AGREE II instrument with a general content validity index value of 0.93 and through the analysis of applicability with Kappa test analysis, obtaining a value of 0.81, with almost perfect agreement. Conclusion: The protocol was structured with quality to guide the nursing team in assisting burned patients. Therefore, its use is indicated

Objetivo:Construir, validar y evaluar la aplicabilidad de un protocolo de atención de enfermería a pacientes adultos que sufrieron quemaduras en un hospital público de la región Norte de Brasil. Método: Estudio metodológico que siguió los siguientes pasos: construcción del instrumento; validación de contenido utilizando la herramienta de evaluación AGREE II; y análisis de aplicabilidad con cuestionario semiestructurado con el equipo de enfermería y de acuerdo y test KAPPA. Resultados: Desde la etapa de diagnóstico situacional, el protocolo fue elaborado con base en la revisión bibliográfica y validado por los especialistas a través del instrumento AGREE II con un valor de Índice de Validez de Contenido General (IVC) de 0,93 y mediante el análisis de aplicabilidad con el análisis del Test Kappa, obteniendo un valor de 0.81, con concordancia casi perfecta. Conclusión: El protocolo fue estructurado con calidad para orientar al equipo de enfermería en el cuidado del paciente quemado y, por tanto, está indicado su uso.

Saberes e Práticas Sobre Prevenção e Tratamento de Queimaduras no Ambiente Domiciliar / Knowledge and Practices About Prevention and Treatment of Burns in the Home Environment / Conocimientos y Prácticas Sobre Prevención y Tratamiento de Quemaduras en el Ambiente Domiciliario

Objetivos:Demonstrar os saberes e as práticas de indivíduos sobre prevenção e tratamento de queimaduras no ambiente domiciliar e descrever o cuidado educativo de enfermagem na prevenção e tratamento de queimaduras no ambiente domiciliar. Método: Pesquisa convergente-assistencial realizada de maneira virtual, no período de junho a agosto de 2021, com pessoas residentes na cidade de Macaé (RJ). Resultados: A pesquisa incluiu 16 participantes, sendo 81,25% (n = 13) do sexo feminino, com idades entre 19 e 59 anos. Na análise das entrevistas, foi possível identificar saberes e práticas equivocados sobre a prevenção e o tratamento de queimaduras, a serem discutidos neste estudo. Conclusão: Embora haja conhecimento acerca dos saberes e práticas adequados sobre prevenção e tratamento de queimaduras no ambiente domiciliar, houve identificação de práticas equivocadas que podem prejudicar o correto tratamento e prevenção de agravos. Os achados deste estudo apontam para a necessidade de construir materiais e de realizar práticas educativas com essa população para reforço de medidas preventivas de queimaduras.

Objectives:To demonstrate the knowledge and practices of individuals on the prevention and treatment of burns in the home environment and to describe the educational nursing care in the prevention and treatment of burns in the home environment. Method: Convergent care research was carried out virtually, from June to August 2021, with people residing in the city of Macaé/RJ, Brazil. Results: The survey included 16 participants, 81.25% (n = 13) female, aged between 19 and 59 years old. In the analysis of the interviews, it was possible to identify mistaken knowledge and practices about the prevention and treatment of burns, to be discussed in this study. Conclusion: Although there is knowledge about adequate knowledge and practices on the prevention and treatment of burns in the home environment, there was identification of wrong practices that can harm the correct treatment and prevention of injuries. The findings of this study point to the need to build materials and carry out educational practices with this population to reinforce preventive measures for burns.

Objetivos:Demostrar los conocimientos y prácticas de los individuos sobre la prevención y tratamiento de quemaduras en el ambiente domiciliario y describir el cuidado educativo de enfermería en la prevención y tratamiento de quemaduras en el ambiente domiciliario. Método: Investigación de Atención Convergente (PCA) realizada virtualmente, de junio a agosto de 2021, con personas residentes en la ciudad de Macaé/RJ. Resultados: La encuesta contó con 16 participantes, 81,25% (n=13) mujeres, con edades entre 19 y 59 años. En el análisis de las entrevistas, fue posible identificar conocimientos y prácticas erróneas sobre la prevención y el tratamiento de las quemaduras, para ser discutidas en este estudio. Conclusión: Si bien existe conocimiento sobre los saberes y prácticas sobre la prevención y tratamiento de quemaduras en el ámbito domiciliario, se identificaron prácticas incorrectas que pueden perjudicar el correcto tratamiento y prevención de lesiones. Los hallazgos de este estudio apuntan para la necesidad de construir materiales y realizar prácticas educativas con esta población para reforzar las medidas preventivas de quemaduras.

Estimación de factores de riesgo del retardo en la cicatrización en pacientes quemados / Estimation of Risk Factors for Delayed Healing in Burn Patients

Introducción: La atención al paciente con retardo en la cicatrización parte de la optimización en sus cuidados. La reversión del cuadro requiere del conocimiento de los factores de riesgo. La literatura nacional e internacional describen factores locales o relacionados con la herida y generales o relacionados al estado general del paciente. Objetivo: Estimar los factores de riesgo del retardo en la cicatrización en pacientes quemados. Métodos: Estudio analítico de casos y control en pacientes quemados ingresados en el Servicio de Caumatología del Hospital Universitario Manuel Ascunce Domenech en el período 2017 a 2021. La población objeto de estudio comprendió a 267 pacientes. Se calculó el odds ratio y el intervalo de confianza. Resultados: El desarrollo de retardo en la cicatrización resultó tres veces y media más probable en pacientes quemados con 45 años y más, odds ratio 3,591. Además, fue nueve veces más probable en enfermedades crónicas asociadas, hasta seis veces en quemaduras no accidentales, 163 veces en la complicación local y 89 veces en la complicación sistémica. Conclusiones: Los factores de riesgo del retardo en la cicatrización en pacientes quemados identificados fueron los siguientes: edad de 45 años y más, presencia de comorbilidad, el fuego directo como agente causal, el modo de producción no accidental, la presencia de más de seis zonas anatómicas afectadas, la quemadura hipodérmica, la quemadura de 20 porciento de superficie corporal quemada y más de extensión, el apoyo de la lesión, el índice cubano de pronóstico con riesgo vital, la complicación local y la complicación sistémica(AU)

Introduction: The care for the patient with delayed healing starts from the optimization of their care. Reversing such condition requires knowledge of the risk factors. The national and international literature describes local factors related to the injury and general factors related to the patient's general condition. Objective: To estimate the risk factors for delayed healing in burn patients. Methods: An analytical case-control study was carried out with burn patients admitted to the caumatology service at Hospital Universitario Manuel Ascunce Domenech in the period from 2017 to 2021. The study population consisted of 267 patients. Odds ratio and confidence interval were calculated. Results: The development of delayed healing was three and a half times more likely in burn patients aged 45 years or over (odds ratio: 3.591). In addition, it was nine times more likely for associated chronic diseases, up to six times in nonaccidental burns, 163 times in local complications, and 89 times in systemic complications. Conclusions: The identified risk factors for delayed healing in burn patients were the following: age 45 years or over, presence of comorbidity, direct fire as causative agent, nonaccidental way of production, presence of more than six affected anatomical areas, hypodermic burn, burn extension of 20 percent or over on the burned body surface, injury contact pressure, the Cuban index of prognostic vital risk, as well as the local or the systemic complications(AU)

Thermal Injury Protocol to Study Healing, With and Without Infection, in Guinea Pig (Cavia porcellus) Model / Protocolo de Lesión Térmica, para Estudio de Cicatrización, en Modelo Animal Cobayo (Cavia porcellus)

SUMMARY: Experimental healing studies in humans are complex and difficult to replicate in vitro. Hence, animal models are needed to study the different stages involved. The guinea pig (Cavia porcellus) is a model close to human physiology, including the lack of vitamin C synthesis, a precursor of collagen fibers for healing. The thermal injury in this animal makes it possible to study all the stages of healing, taking few days to show tissue repair in the processes with and without localized infection. The aim of this work was to systematize an experimental guinea pig (Cavia porcellus) animal model protocol for studies on healing with and without localized infection.

Los estudios experimentales de cicatrización en humanos son complejos, difícilmente replicables in vitro, por lo que se hace necesarias modelos animales que permitan el estudio de las distintas etapas que ella implica. El cobayo (Cavia porcellus) resulta ser un modelo cercano a la fisiología humana, incluyendo la falta síntesis de vitamina C precursora de fibras colágenas para la cicatrización. La lesión térmica en este animal, permite estudiar todas las etapas de la cicatrización, mostrando pocos días en la reparación tisular, tanto en proceso con y sin infección localizada. El objetivo de este trabajo fue sistematizar un protocolo de modelo animal experimental en cobayo (Cavia porcellus) para estudios de cicatrización con y sin infección localizada.

Perfil de mulheres atendidas em hospital de alta complexidade devido a agressão por queimadura pelo parceiro / Profile of women attended at a high complexity hospital due to assumption due to burning by the partner / Perfil de mujeres atendidas a un hospital de alta complejidad por asunción por quemaduras por parte de la pareja

Objetivo: Descrever o perfil dos atendimentos a mulheres que foram agredidas pelo parceiro íntimo e sofreram queimaduras em hospital de referência em trauma, urgência e emergência do Estado de Minas Gerais. Método: estudo transversal, que analisou prontuários de 19 mulheres vítimas de agressão por queimadura realizadas pelo parceiro íntimo em um hospital de referência em trauma, urgência e emergência no período de 2016 a 2019. Resultados: A maioria das vítimas era parda, casada, com filhos, trabalhava informalmente e foi agredida na residência. O atendimento incluiu prioridade muito urgente/laranja, queimaduras graves de 2º grau, internação, procedimentos cirúrgicos, complicações e acompanhamento ambulatorial pós-alta. Conclusão: Os resultados indicam atendimentos de alta complexidade, o que implica necessidade de os serviços de saúde estabelecerem mecanismos de rastreamento e investigação da violência contra a mulher, bem como preparo da equipe, prevenindo agravamentos e oferecendo suporte adequado

Objective: To describe the epidemiological profile of women who suffered assault due to burns by their intimate partner and were treated at a referral hospital for trauma emergencies in the State of Minas Gerais, Brazil. Method: This cross-sectional study analyzed the medical records of 19 women who were victims of assault due to burns by their intimate partner from 2016 to 2019in a referral hospital for trauma emergencies in Minas Gerais. Results: Most victims were Brown, married, with children, worked informally, and were assaulted at home. Care included very urgent/orange priority treatment, severe second-degree burns, hospitalization, surgical procedures, complications, and post-discharge outpatient follow-up. Conclusion: Health services must establish mechanisms to track and investigate violence against women, preventing the worsening of their condition and offering adequate support. Professionals must be prepared at all levels of care and use surveillance and promotion strategies

Describir el perfil de atención a mujeres que sufrieron agresión por quemaduras por parte de su pareja íntima, atendidas en un hospital de referencia para trauma, urgencia y emergencia en el estado de Minas Gerais (Brasil). Método: estudio transversal, que analizó las historias clínicas de 19 mujeres víctimas de agresión por quemaduras por parte de su pareja íntima atendidas en un hospital de referencia de trauma, urgencia y emergencia en Minas Gerais, en el periodo de 2016 a 2019. Resultados: La mayoría de las víctimas eran pardas, casadas, con hijos, trabajaban informalmente y fueron agredidas en su casa. La atención incluyó prioridad muy urgente/naranja, quemaduras graves de segundo grado, hospitalización, procedimientos quirúrgicos, complicaciones y seguimiento ambulatorio posterior al alta. Conclusión: Los resultados muestran una atención de alta complejidad, lo que requiere que los servicios de salud establezcan mecanismos para el seguimiento e investigación de la violencia contra la mujer, así como una mejor preparación de los profesionales para prevenir los agravamientos y ofrecer una adecuada asistencia

O sofrimento, a depressão e o impacto na autoimagem em indivíduos com queimaduras / Suffering, depression, and the impact on self-image in individuals with burns

Fundamentos: Indivíduos com queimaduras sofrem com autoestima e depressão. Objetivo: Analisarpercepção dos participantes quanto ao sofrimento ocasionado pela queimadura, sintomatologia depressiva e interferência na autoimagem e relacionamento interpessoal. Métodos: Estudo qualitativo, longitudinal, descritivo, com 36 participantes atendidos em centro de referência a queimados de hospital escola do Sul do Brasil. Realizada entrevista semiestruturada, dados tratados pela Análise de Conteúdo. Resultados: Emergiu categoria sobre o sofrimento causado pela queimadura e impacto na autoimagem com três unidades temáticas. Dados apontam participantes insatisfeitos com autoimagem, desenvolveram sintomatologia depressiva em resposta às dificuldades que queimadura acarretou na vida de relação; apoio familiar foi decisivo ao enfrentamento da nova condição, relações afetivas foram resgatadas a beneficiar a recuperação.Conclusão e implicações para prática: Percepção dos participantes para autoimagem prejudicada associada a autoestima diminuída e sintomatologia depressiva, prejuízo para o relacionamento interpessoale apontam a importância da família no processo de recuperação e fortalecimento dos laços familiares durante e após tratamento da queimadura (AU).

Introduction: Individuals with burns suffer from self-esteem and depression. Objective: Analyze the participants' perception of the suffering caused by the burn, depressive symptoms, and interference in self-image and interpersonal relationships. Methods: Qualitative, longitudinal, descriptive study, with 36 participants seen at a reference center of care to burn people in a teaching hospital in southern Brazil. A semi-structured interview was conducted, and data were processed through Content Analysis. Results: The category about the suffering caused by the burn, and its impact on self-image emerged with three thematic units. Data suggest that participants dissatisfied with a self-image developed depressive symptoms in response to the difficulties that the burn caused in the life of a relationship; family support was decisive in coping with the new condition; affective links were rescued, benefiting the recovery.Conclusion and implications for practice: Participants' self-image perception damaged and associated with decreased self-esteem and depressive symptoms, impairment for the interpersonal relationship, and pointing out the importance of the family in the process of recovery and strengthening of family bonds during and after treatment of the burn (AU).

Fundamentos: Las personas con quemaduras sufren de autoestima y depresión. Objetivo: Analisar la percepción de los participantes sobre el sufrimiento causado por la quemadura, sintomatología depresiva y su interferencia en auto imagen e en el relacionamiento interpersonal. Métodos: estudio cualitativo, d longitudinal, descriptivo, con 36 participantes atendidos en un centro de quemados de un hospital universitario del sur de Brasil. Se realizó una entrevista semiestructurada, los datos fueron tratados por Análisis de Contenido. Resultados: La categoría sobre el sufrimiento provocado por la quemadura y el impacto en la autoimagen surgió con tres unidades temáticas. Los datos indican que los participantes insatisfechos con la imagen de sí mismos, desarrollaron síntomas depresivos en respuesta a las dificultades que la quemadura les causó en la vida de pareja; El apoyo familiar fue determinante para afrontar la nueva condición, se rescataron las relaciones afectivas en beneficio de la recuperación. Conclusión e implicaciones para la práctica: La percepción de los participantes de la autoimagen deteriorada asociada a disminución de la autoestima y síntomas depresivos, deterioro para el relacionamiento interpersonal y señalan la importancia de la familia en el proceso de recuperación y fortalecimiento de los lazos familiares durante y después. tratamiento de la quemadura (AU).

Frequência de sintomas sugestivos de transtorno de estresse agudo em pacientes queimados / Frequency of symptoms suggestive of acute stress disorder in burn patients / Frecuencia de síntomas sugestivos de trastorno de estrés agudo en pacientes quemados

As queimaduras são um sério problema de saúde pública devido aos altos custos financeiros e aos impactos físicos, psicológicos e sociais nos indivíduos afetados. Este artigo apresenta um estudo transversal, que investigou a possível ocorrência do transtorno de estresse agudo em pacientes vítimas de queimaduras, a partir do levantamento de sintomas sugestivos do transtorno em pacientes hospitalizados em uma unidade de queimados, com base em uma amostragem não probabilística e de conveniência. Os resultados indicaram que a margem de transtorno de estresse agudo em pacientes que foram internados na unidade de queimados da instituição estudada está próxima à prevalência prevista pelo Manual Diagnóstico e Estatístico de Transtornos Mentais, que é de 10%. A pesquisa mostra a importância de se considerar os impactos psicológicos das queimaduras e a necessidade de políticas públicas que possam ajudar a prevenir e tratar esses transtornos em pacientes afetados.

Burns are a serious public health problem due to the high financial costs and physical, psychological, and social impacts on affected individuals. This article presents a cross-sectional study that investigated the possible occurrence of acute stress disorder in burn patients by assessing symptoms suggestive of the disorder in patients hospitalized in a burn unit, based on a non-probabilistic convenience sample. The results indicated that the rate of acute stress disorder in patients admitted to the burn unit of the institution studied is close to the prevalence predicted by the Diagnostic and Statistical Manual of Mental Disorders, which is 10%. The research highlights the importance of considering the psychological impacts of burns and the need for public policies to prevent and treat these disorders in affected patients.

Las quemaduras representan un grave problema de salud pública debido a los altos costos financieros y a los impactos físicos, psicológicos y sociales en las personas afectadas. Este artículo presenta un estudio transversal que investigó la posible presencia de trastorno de estrés agudo en pacientes víctimas de quemaduras, mediante la evaluación de síntomas sugestivos del trastorno en pacientes hospitalizados en una unidad de quemados, utilizando una muestra no probabilística y de conveniencia. Los resultados indicaron que la tasa de trastorno de estrés agudo en pacientes ingresados en la unidad de quemados de la institución estudiada se encuentra cercana a la prevalencia prevista en el Manual Diagnóstico y Estadístico de Trastornos Mentales, que es del 10%. La investigación resalta la importancia de considerar los impactos psicológicos de las quemaduras y la necesidad de políticas públicas que puedan contribuir a prevenir y tratar estos trastornos en los pacientes afectados.

Boletín Epidemiológico Semana 51 (Periodo de Vacaciones de Fin de Año) / Epidemiological Bulletin Week 51 (Year-End Holiday Period)

Principales causas de consulta, acumuladas desde el 24 de diciembre a la fecha, años 2020 ­ 2021. Situación de quemados fechas de quemaduras 1º dic ­ 2 de enero 2019 ­ 2022. Proporción de quemaduras por pólvora divididos por menores y mayores de 18 años de edad, 24 de dic 2022 al 2 de enero de 2023. Quemaduras por pólvora por grupo de edad, comparativo 24 de diciembre de 2022 al 2 de enero de 2023, datos del mismo periodo 2019 y 2021. Quemaduras por pólvora por departamento, comparativo 24 de diciembre de 2022 al 2 de enero de 2023, datos del mismo periodo 2019 y 2021. Áreas lesionadas en personas con quemaduras por productos pirotécnicos por sitio anatómico, El Salvador 24 de diciembre de 2022 al 2 de enero de 2023: Datos generales sobre quemaduras por pólvora 24 de diciembre de 2022 al 2 de enero de 2023, Quemaduras por pólvora plan de fin de año El Salvador 24 de diciembre de 2022 al 2 de enero de 2023, por pirotécnico implicado, Total de consultas, emergencias y referencias, plan de fin de año El Salvador 2019 ­ 2022

Main causes of consultation, accumulated from December 24 to date, years 2020 - 2021. Situation of burns dates of burns Dec 1 - Jan 2, 2019 - 2022. Proportion of gunpowder burns divided by minors and majors under 18 years of age. age, December 24, 2022 to January 2, 2023. Gunpowder burns by age group, comparison December 24, 2022 to January 2, 2023, data from the same period 2019 and 2021. Gunpowder burns by department, comparison 24 from December 2022 to January 2, 2023, data from the same period 2019 and 2021. Injured areas in people with burns from pyrotechnic products by anatomical site, El Salvador December 24, 2022 to January 2, 2023: General data on burns by gunpowder December 24, 2022 to January 2, 2023, Burns by gunpowder year-end plan El Salvador December 24, 2022 to January 2, 2023, by pyrotechnician involved, Total consultations, emergencies and referrals, plan d The end of the year El Salvador 2019 ­ 2022

Taxa de falha em enxertos de pele em pacientes queimados e fatores relacionados / Failure rate in skin grafts in burn patients and related factors / Tasa de fracasso en injertos de piel en pacientes quemados y factores relacionados

Objetivo: Estimar a taxa de falha dos enxertos de pele em pacientes com queimaduras e os fatores relacionados. Método: Trata-se de um estudo de abordagem quantitativa, longitudinal, do tipo coorte prospectiva, realizado com pacientes vítimas de queimadura submetidos a procedimento cirúrgico de enxertia de pele. A coleta de dados foi realizada por meio de entrevistas, análise de prontuário e avaliação dos enxertos. Resultados: O tempo médio de acompanhamento foi de 20,7 dias. Na amostra estudada 41,67% dos pacientes apresentaram falha na adesão da enxertia de pele e os fatores que se mostraram significativos para o sucesso foram: alteração de níveis séricos de albumina; presença de sangramento; presença, quantidade e aspecto de exsudato e presença de odor. Conclusão: Pode-se constatar que aspectos relacionados às condições do leito da ferida são determinantes no sucesso do enxerto de pele.

Objective: To estimate the failure rate of skin grafts in patients with burns and related factors. Method: This is a quantitative, longitudinal, prospective cohort study, carried out with burn victims undergoing skin grafting. Data collection was performed through interviews, analysis of medical records and evaluation of grafts. Results: The mean follow-up time was 20.7 days. In the sample studied, 41.67% of the patients had failed to adhere to skin grafting and the factors that proved to be significant for success were: change in serum albumin levels; presence of bleeding; presence, amount and appearance of exudate and presence of odor. Conclusion: It can be seen that aspects related to the conditions of the wound bed are decisive in the success of the skin graft.

Objetivo: Estimar la tasa de fracasso de los injertos de piel en pacientes con quemaduras y factores relacionados. Método: Se trata de un estudio de cohortes prospectivo, longitudinal, cuantitativo, realizado con víctimas de quemaduras sometidas a injertos de piel. La recolección de datos se realizó a través de entrevistas, análisis de historias clínicas y evaluación de injertos. Resultados: El tiempo medio de seguimiento fue de 20,7 días. En la muestra estudiada, el 41,67% de los pacientes no habían logrado adherirse al injerto de piel y los factores que resultaron significativos para el éxito fueron: cambio en los niveles de albúmina sérica; presencia de sangrado; presencia, cantidad y apariencia de exudado y presencia de olor. Conclusión: Se puede apreciar que los aspectos relacionados con las condiciones del lecho de la herida son determinantes en el éxito del injerto de piel.

Meta-analysis of the effects of xenogeneic acellular dermal matrix dressings in the treatment of wounds in burn patients / 中华烧伤杂志

Objective: To evaluate the efficacy and safety of xenogeneic acellular dermal matrix (ADM) dressings for the treatment of wounds in burn patients. Methods: The meta-analysis method was adopted. Databases including Chinese Journal Full-text Database, Wanfang Database, VIP Database, and Chinese Biomedical Database were retrieved with the search terms in Chinese version of ", , , " and PubMed, Embase, Web of Science, and Cochrane Library were retrieved with the search terms in English version of "xenogeneic acellular dermal matrix, dressing, burn wound, burn" to obtain the publicly published randomized controlled trials on the efficacy of xenogeneic ADM dressings for the treatment of wounds in burn patients from the establishment of each database to December 2021. The outcome indexes included wound healing time, ratio of scar hyperplasia, Vancouver scar scale (VSS) score, ratio of complications, ratio of skin grafting, and ratio of bacteria detection. Rev Man 5.3 and Stata 14.0 statistical softwares were used to conduct a meta-analysis of eligible studies. Results: A total of 1 596 burn patients from 16 studies were included, including 835 patients in experimental group who received xenogeneic ADM dressings therapy and 761 patients in control group who received other methods therapy. The bias risk of all the 16 included studies was uncertain. Compared with those in control group, patients in experimental group had significantly shorter wound healing time, lower VSS scores (with standardized mean differences of -2.50 and -3.10, 95% confidence intervals of -3.02--1.98 and -4.87--1.34, respectively, P values both <0.05), and lower ratios of scar hyperplasia, complications, skin grafting, and bacteria detection (with relative risks of 0.58, 0.23, 0.32, and 0.27, 95% confidence intervals of 0.43-0.80, 0.14-0.37, 0.15-0.67, and 0.11-0.69, respectively, P<0.05). Subgroup analysis showed that the difference of intervention measures in control group might be the source of heterogeneity in wound healing time. There was no publication bias in ratio of scar hyperplasia (P≥0.05), while there was publication bias in wound healing time, VSS score, and ratio of complications (P<0.05). Conclusions: Xenogeneic ADM dressings can shorten the wound healing time of burn patients, reduce the VSS score and the ratios of scar hyperplasia, complications, skin grafting, and bacteria detection.

A prospective study on application of human umbilical cord mesenchymal stem cells combined with autologous Meek microskin transplantation in patients with extensive burns / 中华烧伤杂志

Objective: To investigate the effects of human umbilical cord mesenchymal stem cells (hUCMSCs) combined with autologous Meek microskin transplantation on patients with extensive burns. Methods: The prospective self-controlled study was conducted. From May 2019 to June 2022, 16 patients with extensive burns admitted to the 990th Hospital of PLA Joint Logistics Support Force met the inclusion criteria, while 3 patients were excluded according to the exclusion criteria, and 13 patients were finally selected, including 10 males and 3 females, aged 24-61 (42±13) years. A total of 20 trial areas (40 wounds, with area of 10 cm×10 cm in each wound) were selected. Two adjacent wounds in each trial area were divided into hUCMSC+gel group applied with hyaluronic acid gel containing hUCMSCs and gel only group applied with hyaluronic acid gel only according to the random number table, with 20 wounds in each group. Afterwards the wounds in two groups were transplanted with autologous Meek microskin grafts with an extension ratio of 1∶6. In 2, 3, and 4 weeks post operation, the wound healing was observed, the wound healing rate was calculated, and the wound healing time was recorded. The specimen of wound secretion was collected for microorganism culture if there was purulent secretion on the wound post operation. In 3, 6, and 12 months post operation, the scar hyperplasia in wound was assessed using the Vancouver scar scale (VSS). In 3 months post operation, the wound tissue was collected for hematoxylin-eosin (HE) staining to observe the morphological changes and for immunohistochemical staining to observe the positive expressions of Ki67 and vimentin and to count the number of positive cells. Data were statistically analyzed with paired samples t test and Bonferronni correction. Results: In 2, 3, and 4 weeks post operation, the wound healing rates in hUCMSC+gel group were (80±11)%, (84±12)%, and (92±9)%, respectively, which were significantly higher than (67±18)%, (74±21)%, and (84±16)% in gel only group (with t values of 4.01, 3.52, and 3.66, respectively, P<0.05). The wound healing time in hUCMSC+gel group was (31±11) d, which was significantly shorter than (36±13) d in gel only group (t=-3.68, P<0.05). The microbiological culture of the postoperative wound secretion specimens from the adjacent wounds in 2 groups was identical, with negative results in 4 trial areas and positive results in 16 trial areas. In 3, 6, and 12 months post operation, the VSS scores of wounds in gel only group were 7.8±1.9, 6.7±2.1, and 5.4±1.6, which were significantly higher than 6.8±1.8, 5.6±1.6, and 4.0±1.4 in hUCMSC+gel group, respectively (with t values of -4.79, -4.37, and -5.47, respectively, P<0.05). In 3 months post operation, HE staining showed an increase in epidermal layer thickness and epidermal crest in wound in hUCMSC+gel group compared with those in gel only group, and immunohistochemical staining showed a significant increase in the number of Ki67 positive cells in wound in hUCMSC+gel group compared with those in gel only group (t=4.39, P<0.05), with no statistically significant difference in the number of vimentin positive cells in wound between the 2 groups (P>0.05). Conclusions: The application of hyaluronic acid gel containing hUCMSCs to the wound is simple to perform and is therefore a preferable route. Topical application of hUCMSCs can promote healing of the autologous Meek microskin grafted area in patients with extensive burns, shorten wound healing time, and alleviate scar hyperplasia. The above effects may be related to the increased epidermal thickness and epidermal crest, and active cell proliferation.

Research progress on moderate and deep sedation during wound dressing change in pediatric burn patients / 中华烧伤杂志

Moderate and deep sedation can effectively relieve or eliminate the pain and body discomfort during wound dressing change in pediatric burn patients, relieve anxiety, agitation, and even delirium of the children, reduce the metabolic rate of the children, make them in a quiet, comfortable, and cooperative state, which is conducive to the smooth completion of dressing change. This paper summarized the three aspects of moderate and deep sedation in pediatric burn patients, including the overview, main points of implementation, and effects, and further introduced the moderate and deep sedation medication regimens for different routes of administration, as well as the content of evaluation and monitoring. Suggestions on the prevention and management of related complications and the management of moderate and deep sedation implementation procedures were put forward, in order to provide references for the development of moderate and deep sedation for wound dressing change in pediatric burn patients in China.

A case of skin ulcers secondary to extensive burns caused by flame and heavy metal-containing hydrothermal fluids / 中华烧伤杂志

On May 13, 2020, a 56-year-old man with extensive burns caused by flames and heavy metal-containing hydrothermal fluids was admitted to the General Hospital of Western Theater Command. After being admitted to the hospital, most of the burn wounds healed after treatments such as debridement, expansion, skin grafting, anti-shock, anti-infection, fluid replacement, and wound dressing change, etc. However, in the middle and late stages of treatment, the patient's burn wounds gradually showed repeated skin ulceration and inflammation. After excluding the cause of physical, bacterial infection and others, IgG4-related skin diseases was finally diagnosed by histopathological examination of tissue biopsy and concentration measurement of IgG4 in interstitial fluid, and the condition was improved after hormone treatment. This suggests that extensive burns may lead to the occurrence of autoimmune skin diseases. For the diagnosis of such diseases, it is necessary to combine clinical manifestations, serological examinations, and histopathological biopsy, etc. to avoid diagnostic pitfalls and draw correct conclusions.

Establishment and application of the ten-fold rehydration formula for emergency resuscitation of pediatric patients after extensive burns / 中华烧伤杂志

Objective: To investigate the scientificity and feasibility of the ten-fold rehydration formula for emergency resuscitation of pediatric patients after extensive burns. Methods: A retrospective observational study was conducted. The total burn area of 30%-100% total body surface area (TBSA) and body weight of 6-50 kg in 433 pediatric patients (250 males and 183 females, aged 3 months to 14 years) with extensive burns who met the inclusion criteria and admitted to the burn departments of 72 Class A tertiary hospitals were collected. The 6 319 pairs of simulated data were constructed after pairing each body weight of 6-50 kg (programmed in steps of 0.5 kg) and each total burn area of 30%-100% TBSA (programmed in steps of 1%TBSA). They were put into three accepted pediatric rehydration formulae, namely the commonly used domestic pediatric rehydration formula for burn patients (hereinafter referred to as the domestic rehydration formula), the Galveston formula, and the Cincinnati formula, and the two rehydration formulae for pediatric emergency, namely the simplified resuscitation formula for emergency care of patients with extensive burns proposed by the World Health Organization's Technical Working Group on Burns (TWGB, hereinafter referred to as the TWGB formula) and the pediatric ten-fold rehydration formula proposed by the author of this article--rehydration rate (mL/h)=body weight (kg) × 10 (mL·kg-1·h-1) to calculate the rehydration rate within 8 h post injury (hereinafter referred to as the rehydration rate). The range of the results of the 3 accepted pediatric rehydration formulae ±20% were regarded as the reasonable rehydration rate, and the accuracy rates of rehydration rate calculated using the two pediatric emergency rehydration formulae were compared. Using the maximum burn areas (55% and 85% TBSA) corresponding to the reasonable rehydration rate calculated by the pediatric ten-fold rehydration formula at the body weight of 6 and 50 kg respectively, the total burn area of 30% to 100% TBSA was divided into 3 segments and the accuracy rates of the rehydration rate calculated using the 2 pediatric emergency rehydration formulae in each segment were compared. When neither of the rehydration rates calculated by the 2 pediatric emergency rehydration formulae was reasonable, the differences between the two rehydration rates were compared. The distribution of 433 pediatric patients in the 3 previous total burn area segments was counted and the accuracy rates of the rehydration rate calculated using the 2 pediatric emergency rehydration formulae were calculated and compared. Data were statistically analyzed with McNemar test. Results: Substitution of 6 319 pairs of simulated data showed that the accuracy rates of the rehydration rates calculated by the pediatric ten-fold rehydration formula was 73.92% (4 671/6 319), which was significantly higher than 4.02% (254/6 319) of the TWGB formula (χ2=6 490.88,P<0.05). When the total burn area was 30%-55% and 56%-85% TBSA, the accuracy rates of the rehydration rates calculated by the pediatric ten-fold rehydration formula were 100% (2 314/2 314) and 88.28% (2 357/2 670), respectively, which were significantly higher than 10.98% (254/2 314) and 0 (0/2 670) of the TWGB formula (with χ2 values of 3 712.49 and 4 227.97, respectively, P<0.05); when the total burn area was 86%-100% TBSA, the accuracy rates of the rehydration rates calculated by the pediatric ten-fold rehydration formula and the TWGB formula were 0 (0/1 335). When the rehydration rates calculated by the 2 pediatric emergency rehydration formulae were unreasonable, the rehydration rates calculated by the pediatric ten-fold rehydration formula were all higher than those of the TWGB formula. There were 93.07% (403/433), 5.77% (25/433), and 1.15% (5/433) patients in the 433 pediatric patients had total burn area of 30%-55%, 56%-85%, and 86%-100% TBSA, respectively, and the accuracy rate of the rehydration rate calculated using the pediatric ten-fold rehydration formula was 97.69% (423/433), which was significantly higher than 0 (0/433) of the TWGB formula (χ2=826.90, P<0.05). Conclusions: The application of the pediatric ten-fold rehydration formula to estimate the rehydration rate of pediatric patients after extensive burns is more accurate and convenient, superior to the TWGB formula, suitable for application by front-line healthcare workers that are not specialized in burns in pre-admission rescue of pediatric patients with extensive burns, and is worthy of promotion.

Exploration of family rehabilitation model for children with scar contracture after hand burns / 中华烧伤杂志

Objective: To explore the family rehabilitation model for children with scar contracture after hand burns and observe its efficacy. Methods: A retrospective non-randomized controlled study was conducted. From March 2020 to March 2021, 30 children with scar contracture after deep partial-thickness to full-thickness burns of hands, who met the inclusion criteria, were hospitalized in the Burn Center of PLA of the First Affiliated Hospital of Air Force Medical University. According to the rehabilitation model adopted, 18 children (23 affected hands) were included in a group mainly treated by family rehabilitation (hereinafter referred to as family rehabilitation group), and 12 children (15 affected hands) were included in another group mainly treated by hospital rehabilitation (hereinafter referred to as hospital rehabilitation group). In the former group, there were 11 males and 7 females, aged (4.8±2.1) years, who began rehabilitation treatment (3.1±0.8) d after wound healing; in the latter group, there were 7 males and 5 females, aged (4.6±2.1) years, who began rehabilitation treatment (2.8±0.7) d after wound healing. The children in hospital rehabilitation group mainly received active and passive rehabilitation training in the hospital, supplemented by independent rehabilitation training after returning home; after 1-2 weeks of active and passive rehabilitation training in the hospital, the children in family rehabilitation group received active and passive rehabilitation training at home under the guidance of rehabilitation therapists through WeChat platform. Both groups of children were treated for 6 months. During the treatment, they wore pressure gloves and used hand flexion training belts and finger splitting braces. Before treatment and after 6 months of treatment, the modified Vancouver scar scale, the total active movement of the hand method, and Carroll quantitative test of upper extremity function were used to score/rate the scar of the affected hand (with the difference of scar score between before treatment and after treatment being calculated), the joint range of motion (with excellent and good ratio being calculated), and the function of the affected limb, respectively. Data were statistically analyzed with independent sample t test, equivalence test, Fisher's exact probability test, and Mann-Whitney U test. Results: The differences of scar scores of the affected hands of children in family rehabilitation group and hospital rehabilitation group between after 6 months of treatment and those before treatment were 3.0 (2.0, 7.0) and 3.0 (2.0, 8.0) respectively (with 95% confidence interval of 2.37-5.38 and 1.95-5.91). The 95% confidence interval of the difference between the differences of the two groups was -2.43-2.21, which was within the equivalent boundary value of -3-3 (P<0.05). The excellent and good ratios of joint range of motion of the affected hand of children in family rehabilitation group and hospital rehabilitation group were 3/23 and 2/15 respectively before treatment, and 15/23 and 12/15 respectively after 6 months of treatment. The ratings of joint range of motion of the affected hand of children in family rehabilitation group and hospital rehabilitation group after 6 months of treatment were significantly higher than those before treatment (with Z values of 3.58 and 2.30, respectively, P<0.05), but the ratings of joint range of motion of the affected hand between the two groups were similar before treatment and after 6 months of treatment (with Z values of 0.39 and 0.55, respectively, P>0.05). The functional ratings of the affected limbs of children in family rehabilitation group and hospital rehabilitation group after 6 months of treatment were significantly higher than those before treatment (with Z values of 3.98 and 3.51, respectively, P<0.05), but the functional ratings of the affected limbs between the two groups were similar before treatment and after 6 months of treatment (with Z values of 1.27 and 0.38, respectively, P>0.05). Conclusions: The WeChat platform assisted rehabilitation treatment with mainly family rehabilitation, combined with hand flexion and extension brace can effectively reduce the scarring after children's hand burns, improve the joint range of motion of the affected hands, and promote the recovery of affected limb function. The effect is similar to that of hospital-based rehabilitation providing an optional rehabilitation, treatment method for children who cannot continue to receive treatment in hospital.